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Oncology

Density increase a marker of breast cancer risk during HRT
Change in mammographic density may be a useful intermediate marker of increased breast cancer risk in postmenopausal women using estrogen and progestin therapy (EPT). This was the finding of a case-controlled study conducted as part of the Women’s Health Initiative (WHI) study.
Bevacizumab a boon to ovarian cancer patients
Initial combo treatment plus maintenance therapy boosts progression-free survival

New biopsy key in guiding treatment of metastatic cancer
Sentinel node histology not useful in predicting breast cancer survival

Major trial looking at immunohistochemistry does not support use of sophisticated test in guiding treatment
‘Powerful drug’ boosts melanoma survival

Monoclonal antibody ipilimumab a rare success, but some patients die from the treatment
Bisphosphonates unlikely to cause esophageal cancer
Targeted agent looks promising in treating pediatric brain cancer

Drug works on ‘Sonic hedgehog pathway’ found in medulloblastomas, other cancers
Clinical Notes: Canadian testicular cancer guidelines

Guidelines developed on diagnosis, management of germ cell testicular cancer.
X-ray absorptiometry an option for breast density evaluation
Statins may cut prostate cancer recurrence risk

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