Managing severe Alzheimer's diseaseCanadian evidence-based guidelines support the use of a cholinesterase inhibitor or memantine, or both drugs for the management of patients with severe Alzheimer's disease. Enzymes offer promise as targets for treating progressive MS Aneurysm size, site are main predictors of rupture Larger aneurysms and those in posterior circulation at highest risk, with age and comorbidities other key factors First Previous 58 59 60